Advancing Mental Health Through Innovative Research
A leading research laboratory dedicated to developing breakthrough treatments for treatment-resistant neuropsychiatric disorders through neuromodulation and genomic medicine.
300 68th Street SE
Grand Rapids, MI 49548
616.980.7516
research@pinerest.org
Monday – Friday
10:00am – 5:00pm
Collaborative Research Excellence
Our work is made possible through partnerships with leading research and clinical institutions.
Michigan State University
Pine Rest Mental Health
Van Andel Research Institute
Our Mission
Hope Through Science
Psychiatry and behavioral medicine stand at the crossroads of human complexity, where the biological, psychological, social, and emotional dimensions of health converge. What makes this field so deeply compelling is its vast potential to transform lives. Unlike many other disciplines, psychiatry touches every part of the human experience, from the most intricate neural circuits to the broadest societal challenges.
Hope fuels resilience and our ability to bounce back from adversities through harmonic dynamic engagement between our biology and genomics on one hand, and our environment and experiences on the other.
Our laboratory is dedicated to breaking new ground by shattering stigmas, advancing the frontiers of neuroscience, and delivering person-centered care that is as innovative as it is compassionate. We pursue discovery through world-class research infrastructure and collaborative partnerships, aiming to unravel the mysteries of the human mind and translate our findings into therapeutics that directly improve the lives of individuals and communities.
The modern-day boundaries of our field span basic science and molecular biology, mitochondriopathies, electrophysiology, neuromodulation and neuroscience, genomics, to human behavior, emotions, and humanitarian sciences.
Research Focus Area
Pioneering approaches to understanding and treating neuropsychiatric disorders.
Neuromodulation
Investigating novel brain stimulation therapies including Low Amplitude Seizure Therapy (LAP-ST), Transcranial Magnetic Stimulation (TMS), Electroconvulsive Therapy (ECT), Magnetic Seizure Therapy (MST), and Deep Brain Stimulation (DBS) to reduce cognitive side effects while maintaining therapeutic efficacy.
Genomic Medicine
Utilizing genomic and epigenetic tools to understand disease mechanisms, predict treatment response, and develop personalized therapeutic approaches for treatment-resistant conditions.
Mood Disorders
Comprehensive research on depression, bipolar disorder, and treatment-resistant mood conditions, with focus on identifying diagnostic biomarkers and optimizing therapeutic interventions.
Biomarker Discovery
Developing and validating diagnostic and prognostic biomarkers to predict treatment response, identify at-risk populations, and guide personalized treatment selection.
Suicide Prevention
Investigating the rapid anti-suicidal effects of novel interventions and identifying biological and clinical markers to improve risk assessment and prevention strategies.
Resilience Research
Exploring mechanisms of psychological resilience and developing interventions to boost adaptive responses to stress and adversity.